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Definition - What does transdermal mean?

Transdermal refers to the application of a medicinal substance from an adhesive patch placed on the skin, delivering small doses through the pores for rapid absorption into the bloodstream. The skin is comprised of three layers called the epidermis (top layer), dermis (second layer) and the hypodermis (third layer). Transdermal therapy is an effective method of treatment for certain medication types, based on the rich blood supply underlying the layers of skin allowing for quick distribution of a medication.

SureHire explains transdermal

Transdermal application is a common and less invasive means to administer medication. The benefit of using transdermal drugs is that they circumvent the digestive tract and liver where the metabolic decomposition reduces overall effectiveness of ingested capsules, lozenges, pills, and tablets. Transdermal delivery also allows for a steady stream of a lower dose of medication rather than periodic larger doses. This can equalize the medication in the bloodstream.

Transdermal assimilation incorporates discrete modes of therapeutic intervention including microneedles treatment and home gel solutions. Transdermal patches are an alternative form of prescribed therapy, however, overdoses can occur if the material is ripped or chewed on.

Transdermal application measures are employed also in drug testing procedures. Sweat patch testing, for instance, is an optional technique in targeting drug use in employees. This form of transdermal application is preferred by many employers given its tamper-resistant quality, minimizing risk of cheating during drug screen examinations.

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