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Definition - What does Immunogenicity mean?

Immunogenicity is the ability of an agent, such as an epitope or an antigen, to illicit an immune response within the body. This can have both therapeutic and adverse consequences. Immunogenicity can also be categorized as the degree to which the foreign substance has elicited an immune response within the body and can be measured in things such as immunoassay drug testing.

SureHire explains Immunogenicity

Immunogenicity can be used in drug testing and in therapeutic medicine. For example, using a vaccine for certain illnesses to produce an immune response in the body that teaches the body to fight off that specific illness. Immunogenicity can also cause the immune system to react against a drug being used for therapeutic purposes, triggering the immune system to produce anti-drug antibodies, which in turn can nullify the drug's therapeutic benefits, or even cause unwanted adverse effects in the body. In some cases, laboratory testing can be utilized to anticipate potential immunogenicity.

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